Ready for RNA Library Prep without compromise?

  • Struggling with degraded RNA in your RNA-Seq workflow?
  • Is your RNA library prep producing inconsistent or low-complexity libraries?
  • Watching RNA sequencing costs rise due to failed runs?

Get truCOVERed.

truCOVER® Total RNA Library Prep Kits are built to dominate the toughest RNA challenges, especially degraded RNA and FFPE samples, while supporting RNA-seq workflows with speed, precision, and confidence at scale.

 

REQUEST A TRIAL KIT

 

Stop accepting tradeoffs in your RNA library prep workflow.

With truCOVER Total RNA Library Prep Kits, you can:

  • Detect gene fusions with confidence across standard RNA-seq analysis workflows
  • Generate superior, strand specific RNA sequencing libraries with uniform whole transcriptome coverage and minimal duplication
  • Harness Adaptive Focused Acoustics® (AFA®) Technology for RNA library preparation with precise, reproducible fragmentation and controlled insert size
  • Recover more from less: Optimized for 10–500 ng input and degraded RNA (DV200 ≥30%), including FFPE and low-input applications
  • Reduce hands on time by up to 40% with a streamlined, automation ready RNA-seq workflow
  • Capture high proportion of exonic reads (~40%), giving high value data for differential gene expression
  • Drive rRNA down to <1% of reads, maximizing usable sequencing data and lowering cost per sample

An Optimized RNA Library Prep Workflow for Degraded and Low-Input RNA

From Complex Samples to Clean Data – Better. Faster. Easier.

truCOVER Total RNA Library Prep Kits eliminate workflow variability in your RNA-seq workflow, reduces RNA sequencing waste, and empowers your lab to move from troubleshooting to throughput.

 

Let’s Optimize Your RNA-seq Workflow

Tell us about your sample type, input amount, and sequencing goals.
Our experts will provide tailored guidance to optimize your RNA library prep and maximize your RNA-seq performance.

It’s time to stop adapting to your samples — and start controlling them.

DOWNLOAD THE TECHNICAL NOTE:

  
Whole Transcriptome Sequencing from Degraded FFPE Samples: A Fast Workflow to Deliver Robust Gene Fusion Detection

 

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Simplified workflow reduces turnaround time by up to 40%.
 
By utilizing a single-enzyme, single-incubation step for cDNA synthesis and optimizing magnetic bead clean-ups, the protocol reduces workflow time to approximately 4 hours.
 
Confident gene fusion detection.
 
Qubit/qPCR Conversion Rate Chart
truCOVER detected all gene fusions and alternatively spliced RNAs in the Seraseq® FFPE Tumor Fusion RNA Reference Material, at a depth of only 25M reads (typical kits require 50M+ reads).