Capillary blood collection devices may be used in research to obtain small volumes of blood without traditional venipuncture. However, collecting the sample is only the first step; preserving analytes and efficient extraction and purification of biomolecules from small-volume samples is critical for reliable downstream molecular analysis. The truCOLLECT device combines capillary blood collection (fingerstick) with active sample stabilization and is also a key component of a broader, optimized extraction and purification workflow. This optimized workflow approach enables higher yield recovery of analytes from stabilized blood samples, suitable for applications such as genomic DNA analysis, while also supporting greater laboratory efficiency and automation capability.

Dried blood spot (DBS) cards have historically been used for small-volume blood collection in research studies, but the drying process and extraction methods can limit analyte recovery and introduce variability in downstream molecular analysis. In addition, DBS approaches may provide limited suitability for genomic workflows due to challenges in recovering consistent, high-quality DNA from dried blood. The truCOLLECT Solution enables stabilized capillary blood collection and controlled rehydration prior to extraction, supporting broader analyte recovery and more consistent genomic DNA analysis for modern molecular workflows.

Distributed research programs often require complex sample collection, transport, and processing workflows. Stabilized capillary blood collection enables samples to be collected remotely and transported at ambient temperature prior to extraction. By reducing the need for immediate processing and specialized handling, approaches such as the truCOLLECT Solution can simplify study logistics and help lower operational costs associated with sample transport and processing while maintaining compatibility with downstream molecular workflows.