Covaris

Venipuncture quality, Fingerstick simplicity, Lab-ready automation.

The truCOLLECT^® Solution optimizes decentralized genomics studies by combining whole blood integrity, simple self-collection, and ambient logistics.

Learn about:

The challenges associated with traditional venous blood collection for genomic studies in pediatric and neurodevelopmental populations.
The truCOLLECT fingerstick collection workflow, including sample handling, room-temperature stability, and downstream DNA extraction.
A comparison of DNA quality, yield, and integrity obtained from the truCOLLECT fingerstick samples versus venous blood samples.
The feasibility of using truCOLLECT-derived DNA for whole genome sequencing, including long-read sequencing applications.
Use cases for truCOLLECT blood collection kit in rural, remote, and community-based research settings, including self-collection models.
How the truCOLLECT Solution can improve research participation, equity, and scalability in genomic studies over phlebotomy or other remote sampling methods.

More participants. Simpler logistics. Better genomic data.

Watch the Webinar:

Fingerstick-based DNA Collection Using truCOLLECT Solution for WGS in Pediatric & Neurogenetic Research

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Consistent DNA Quality and Quantity

The truCOLLECT Solution enables reliable and consistent DNA recovery from samples stored at room temperature (100% across cohort size of 94).

Stability at ambient temperature minimizes pre-analytical variability, which is common to other sample collection methods.

DNA Stability Over Time

Whole blood samples processed with the truCOLLECT Solution maintain consistent DNA quantity and quality across multiple donor samples after storage at room temperature for 3-6 months (DNA quantity correlated with white blood cell counts).

Samples also demonstrated stability across extreme temperature conditions (50-75° C)

truCOLLECT Solution FAQs

How does the truCOLLECT device compare to other devices used for small-volume blood collection in research?

Capillary blood collection devices may be used in research to obtain small volumes of blood without traditional venipuncture. However, collecting the sample is only the first step; preserving analytes and efficient extraction and purification of biomolecules from small-volume samples is critical for reliable downstream molecular analysis. The truCOLLECT device combines capillary blood collection (fingerstick) with active sample stabilization and is also a key component of a broader, optimized extraction and purification workflow. This optimized workflow approach enables higher yield recovery of analytes from stabilized blood samples, suitable for applications such as genomic DNA analysis, while also supporting greater laboratory efficiency and automation capability.

How does truCOLLECT compare to dried blood spot cards (DBS)?

Dried blood spot (DBS) cards have historically been used for small-volume blood collection in research studies, but the drying process and extraction methods can limit analyte recovery and introduce variability in downstream molecular analysis. In addition, DBS approaches may provide limited suitability for genomic workflows due to challenges in recovering consistent, high-quality DNA from dried blood. The truCOLLECT Solution enables stabilized capillary blood collection and controlled rehydration prior to extraction, supporting broader analyte recovery and more consistent genomic DNA analysis for modern molecular workflows.

How can stabilized remote blood collection reduce study logistics costs?

Distributed research programs often require complex sample collection, transport, and processing workflows. Stabilized capillary blood collection enables samples to be collected remotely and transported at ambient temperature prior to extraction. By reducing the need for immediate processing and specialized handling, approaches such as the truCOLLECT Solution can simplify study logistics and help lower operational costs associated with sample transport and processing while maintaining compatibility with downstream molecular workflows.

The truCOLLECT Solution enables reliable and consistent DNA recovery from samples stored at room temperature (100% across cohort size of 94).

Stability at ambient temperature minimizes pre-analytical variability, which is common to other sample collection methods.

Whole blood samples processed with the truCOLLECT Solution maintain consistent DNA quantity and quality across multiple donor samples after storage at room temperature for 3-6 months (DNA quantity correlated with white blood cell counts).

Samples also demonstrated stability across extreme temperature conditions (50-75° C)

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