When degraded RNA slows you down, it's time to outperform it.

 

Inconsistent or low-complexity libraries? Rising RNA sequencing costs due to failed runs?


truCOVER® Total RNA Library Prep is built to overcome the toughest RNA challenges, delivering speed, precision, and reliable data at scale.

 

REQUEST A TRIAL KIT

 

No compromises, just results.

  • Detect gene fusions with confidence across standard RNA-seq analysis workflows
  • Capture a higher proportion of exonic reads with >80% mapping to protein-coding regions.
  • Recover more from lower quality or low volume inputs: Optimized for 10–500 ng input, across FFPE (DV200 ≥30%) and whole blood (RIN ≥5)
  • Harness Adaptive Focused Acoustics® (AFA®) Technology for RNA library preparation with precise, reproducible fragmentation and controlled insert size
  • Reduce time by up to 40% with a streamlined, 4-hour, automation compatible RNA-seq workflow
  • Prep whole blood samples with no added hands-on time: >99% globin mRNA depletion via the optional Globin RNA Depletion Module

     

See the data  ►    

 

 

 

 

 

 

 

 

 

 

 

 

 

Looking to reduce DNA prep turnaround time by up to 30%?
truCOVER WGS Library Prep has you covered

DOWNLOAD THE TECH NOTE

Other methods add hours to deplete globin. Ours adds none.
Learn how.

 

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Simplified workflow reduces turnaround time by up to 40%.
 
By utilizing a single-enzyme, single-incubation step for cDNA synthesis and optimizing magnetic bead clean-ups, the protocol reduces workflow time to approximately 4 hours.
 
Confident gene fusion detection.
 
Qubit/qPCR Conversion Rate Chart
truCOVER detected all gene fusions and alternatively spliced RNAs at a depth of only 25M reads (typical kits require 50M+ reads).