Introducing a Combined Solution for Deparaffinization of FFPE Tissues and DNA Shearing

Reduce the risk of tissue damage and deliver faster results when extracting nucleic acids from fixed formalin paraffin-embedded (FFPE) tissue samples.

Using the high-throughput Covaris R230 Focused-ultrasonicator together with truXTRAC® FFPE SMART Solutions, your lab can extract DNA and RNA from these precious specimens without harmful chemicals and fragment the samples with the same device—all in an automated workflow.

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R230 Focused Ultrasonicator

Flexible, high-throughput, and automatable DNA and
RNA shearing

  • Gold Standard Mechanical Shearing
    Get the best coverage and sequencing performance—regardless of concentration, sample origin, and purification method.
  • Simplified Workflow
    Seamlessly integrates with major liquid handlers—on deck or on bench—and leading library prep kits.
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truXTRAC® FFPE SMART Solutions

Deparaffinization, extraction, and purification of nucleic acids from FFPE samples

  • Highest FFPE Sample Integrity
    Reduce risk of contamination with an automated workflow and avoid nucleic acid degradation common with toxic solvents.
  • Extract RNA & DNA Simultaneously
    Speed up processing time and standardize sample prep across multiple applications.

See How Covaris Solutions Fit into Your Lab

All about the R230 Focused Ultrasonicator

truXTRAC® FFPE SMART Solutions

The Evolution of Precision Diagnostics in Advancing Treatment Strategies of Solid Tumors

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The Covaris process eliminates the need for xylene-based paraffin removal and reduces the impact of high wax-tissue ratios…. Most importantly, the extracted DNA and RNA performs exceptionally well across a number of downstream applications, including next-generation sequencing.

  • - Jeffrey Conroy
  • Head of Science, OmniSeq Inc.
  • Executive Director, LabCorp

What does end-to-end CGP sample prep with AFA technology look like?

Can be fully integrated
with most liquid handler
platforms or used standalone

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Add-on, automatable solution for active deparaffinization, extraction, and purification of high-quality DNA and RNA

Easy-to-use method editor so techs can hit run and go

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Can be fully integrated with the most liquid handler platforms or used standalone

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Automatable solution for active deparaffinization, extraction, and purification of high-quality DNA and RNA

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Easy-to-use method editor so
techs can hit run and go

Need Less Throughput?

We have a range of instruments using the same, gold-standard AFA technology.

Find the Covaris solution that best meets the needs of your lab.

SPEAK TO A CONSULTANT
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Beyond CGP

Covaris Focused-ultrasonicators, like the R230, can be used across a variety of sample types and applications, making one instrument incredibly versatile.
Learn about Covaris for Germline applications →

Related Resources

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POSTER

Total Nucleic Acids (tNA) Extraction from FFPE Samples Using AFA® Technology

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APP NOTE

Tumor Tissue Evaluation with the Illumina® TruSight™ Oncology 500 (NGS) Assay using the Covaris R230 …

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SOLUTION BRIEF

Covaris truXTRAC® FFPE SMART Solutions

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Solution Brief

truXTRAC® FFPE Total Nucleic Acid Kits