Labs today contend with many challenges when preparing samples for next generation sequencing (NGS), including suboptimal specimens, contamination risk, and complicated workflows.
Covaris Adaptive Focused Acoustics (AFA) Technology is the gold standard in sample preparation for NGS, protein and -omics workflows—delivering better coverage and sequencing performance than enzyme fragmentation, even from poor biospecimens.
Explore this site to see how our AFA technology-based instruments, and associated kits and consumables, significantly improve the quality, yield, and efficiency of sample prep for germline testing, and of the extraction and fragmentation of DNA & RNA from FFPE samples for genomic profiling.
Explore Covaris for Germline Testing → Explore Covaris for CGP →
Greater Fragmentation Precision:
Ensure sample-to-sample reproducibility, regardless of sample type, quality and size.
Reduced Contamination Risk:
Non-contact sample processing leads to fewer opportunities for cross-contamination.
Accurate Results from Poor Samples:
Physical shearing using AFA achieves more uniform results than enzymatic fragmentation.
Flexibility for Variable Batch Sizes:
Process anywhere from 1 to 384 samples without compromising quality or efficiency.
Standardized Workflows:
Reduce hands-on time with automation-friendly instruments that can be integrated with most liquid handlers.
One Workflow Across Sample Types:
Extract and shear DNA and RNA from blood, saliva, cell line, FFPE and other sample types.
AFA ultrasonic energy processes samples by precisely controlling the creation and collapse of millions of cavitation bubbles within the closed sample vessel. This precision enables superior uniformity and higher quality data, even from poor biospecimens.
Achieve cost-effective and high-capacity DNA and RNA
sample preparation—even from low quality or small samples.
Get more information from FFPE tissues—even with low inputs—for faster, more reproducible genomic profiling assays.
